Two routes
Transperineal biopsy passes through the skin between the scrotum and anus. Transrectal biopsy passes through the rectal wall. Either may be paired with MRI targeting and systematic sampling.
Compare practical details
Ask about the expected anesthesia, antibiotic plan, urinary-retention risk, bleeding instructions, recovery restrictions, and who to call after hours.
Know the warning signs
Your procedure team should give you written instructions about fever, inability to urinate, heavy bleeding, worsening pain, and other reasons to seek urgent care.
Bring these questions
Make the next appointment concrete.
- Why do you recommend this route for me?
- What anesthesia will be used?
- How do you reduce infection and retention risk?
- What symptoms require an urgent call?
Sources and further reading
These primary references support the reviewed guide. They do not replace guidance from your own clinician.